@phdthesis{(CRISUNS)36487,
	title = {Biopotential and chemical characterization of extracts and essential oils of species from Juniperus L. genus (Cupressaceae).},
	title[SR] = {Biopotencijal i hemijska karakterizacija ekstrakata i etarskih ulja vrsta roda Juniperus L. (Cupressaceae).},
	abstract = {<p> Characterization of methanol extracts and essential oils of eight Juniperus L. species included phytochemical screening and evaluation of antioxidant, anti-inflammatory and antimicrobial activity. The presence and content of phenolics and terpenoids was confirmed by LC-MS/MS and GC-MS technique. Antioxidant activity of extracts and essential oils (radical scavenger capacity, reduction potential and inhibition of lipid peroxidation) was examined by spectrophotometric methods. With the intention to evaluate anti-inflammatory activity, an ex vivo method was applied to measure activity of platelet cyclooxygenase-1 and 12-lipoxygenase. Antimicrobial activity was evaluated according to six bacterial strains. Examined extracts and essential oils showed noticeable biological activity.</p>},
	abstract[SR] = {<p>Karakterizacija metanolnih ekstrakata i etarskih ulja iglica i &scaron;i&scaron;arki osam vrsta samoniklih kleka (rod Juniperus L.) obuhvatala je fitohemijski skrining i ispitivanje antioksidantne, antiinflamatorne i antimikrobne aktivnosti. Primenom LC-MS/MS i GC-MS tehnike detektovan i odreĎen je sadržaj fenolnih i terpenoidnih sekundarnih biomolekula. Antioksidantna aktivnost ekstrakata i etarskih ulja (sposobnost neutralizacije slobodnih radikala, redukcioni potencijal i inhibicija lipidne peroksidacije) ispitana je primenom spektrofotometrijskih metoda. U cilju odreĎivanja antiinflamatornog potencijala, primenjena je ex vivo metoda za praćenje aktivnosti trombocitne ciklooksigenaze-1 i 12-lipoksigenaze. Antimikrobna aktivnost etarskih ulja odreĎena je na &scaron;est odabranih bakterijskih sojeva. Ispitani ekstrakti i etarska ulja pokazali su značajnu biolo&scaron;ku aktivnost.</p>},
	keywords = {extracts
		essential oils
		needless
		cones
		phenolics
		terpenoids
		antioxidant activity
		anti-inflammatory activity
		antimicrobial activity},
	keywords[SR] = {Juniperus L.
		ekstrakti
		etarska ulja
		iglice
		šišarke
		fenoli
		terpenoidi
		antioksidantna aktivnost
		antiinflamatorna aktivnost
		antimikrobna aktivnost},
	author = {Marija Lesjak},
	year = {2011},
	doi = {10.2298/NS20111123LESJAK},
	publisher = {Author reprint},
	institution = {Faculty of Sciences at Novi Sad},
	institution[SR-CYR] = {Природно-математички факултет у Новом Саду},
	institution[SR] = {Prirodno-matematički fakultet u Novom Sadu}
}